Preliminary study of community-acquired Staphylococcus aureus infection in Manaus Hospital, Amazonia Region, Brazil Estudo preliminar das infeccões por Staphylococcus aureus na comunidade de um Hospital em Manaus, Região do Amazonas, Brasil

نویسندگان

  • Jesus M. Egido
  • Marcus L. Barros
چکیده

Methicillin resistant Staphylococcus aureus is considered a public health problem with a strong potential for dissemination and high rates of morbidity and mortality. In this study we describe bacteriological and epidemiological characteristics of Staphylococcus aureus in Manaus (Amazon region). During the one-year study period (2000-2001), sixteen cases of acute pyogenic multiple abscess were evaluated. Community-acquired S. aureus was identified as causative agent in 10 (62.5%) patients. The strains tested with antimicrobials by discs diffusion method, exhibited a high rate of sensitivity to cephalexin (100%), erythromycin (90%). Oxacillinsusceptible Staphylococcus aureus was 90%. No isolate was resistant to Vancomycin. To our knowledge, no series of community-acquired Staphylococcus aureus in Manaus hospital has been published. Our partial results showed a high rate of antimicrobial sensitivity among community-acquired Staphylococcus aureus in the hospital of Tropical Medicine Institute of Manaus, Amazon Region. Key-words: Community-acquired Staphylococcus aureus. Methicillin resistant. Manaus hospital. Resumo O Staphylococcus aureus resistente a meticilina é considerado como um problema na saúde publica por seu grande potencial de disseminação e altas porcentagens de morbidade e mortalidade. No estudo descrevemos as características bacteriológicas e epidemiológicas do Staphylococcus aureus na cidade de Manaus. No período de um ano (2000-2001) avaliou-se dezesseis casos de abscessos piogênicos múltiplos. Em 10 (62,5%) doentes o agente causal foi identificado como Staphylococcus aureus adquirido na comunidade O estudo das bacterias isoladas frente aos diferentes antimicrobianos, seguindo o método de difusão em disco, mostrou boa sensibilidade a cefalexina (100%) e eritromicina (90%). Noventa porcento dos Staphylococcus aureus isolados foram sensíveis ao oxacilina. Nenhum dos isolados mostrou ser resistente a Vancomicina. Não temos informações sobre publicações dos Staphylococcus aureus adquiridos na comunidade em hospitais de Manaus. Nossos resultados parciais mostram uma alta sensibilidade dos Staphylococcus aureus adquiridos na comunidade aos antimicrobianos, em pacientes internados no Instituto de Medicina Tropical do Manaus, na Região da Amazônia brasileira. Palavras-chaves: Staphylococcus aureus adquirido na comunidade. Resistência a meticilina. Hospitais de Manaus. 1. Clínica de Infectologia Médica da Fundação de Medicina Tropical do Amazonas, Manaus, AM, Brasil. Address to: Dr. Jesus M. Egido. FMTAM. Av. Pedro Teixeira 25. 69040-000 Manaus, AM. Brazil. e-mail: [email protected] Recebido para publicação em 24/9/2002 Aceito em 28/8/2003 Oxacillin-resistant Staphylococcus aureus (ORSA) infection and vancomycin-resistant Staphylococcus aureus (VRSA) infection are an important cause of hospital morbidity and mortality. We report sixteen isolations of Gram positives rods of patients who showed clinical symptomatology of infections and received hospital treatment. The bacteriological isolates were identified. We found ten isolations of Staphylococcus aureus. These strains were tested against 12 different antimicrobial agents by standardized discs diffusion. They showed highest rates of sensitivity to cephalexin, erythromycin and oxacillin. The sixty percent of patients with Staphylococcus aureus infection, described in this report, were initially treated empirically with oxacil l in. All patients recovered completely.

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تاریخ انتشار 2004